Ingredients

UPNEEQ ® (oxymetazoline hydrochloride ophthalmic solution), 0.1%

contains oxymetazoline hydrochloride, an alpha adrenoceptor agonist. UPNEEQ ® is an aseptically prepared, sterile, nonpreserved ophthalmic solution. Each mL of UPNEEQ ® (oxymetazoline hydrochloride ophthalmic solution) 0.1% contains 1 mg of oxymetazoline hydrochloride, equivalent to 0.09 mg (0.09%) of oxymetazoline free base. The ophthalmic solution contains the following inactive ingredients: calcium chloride, hydrochloric acid (used to adjust pH to 5.8 to 6.8), hypromellose, magnesium chloride, potassium chloride, sodium acetate, sodium chloride, sodium citrate, and water for injection.